*Applies to TOTAL® spherical and multifocal contact lenses only. ** Based on in vitro measurements of unworn lenses. *** Based on in vitro studies on delefilcon A sphere lenses wherein wettability was measured using the iDDrop System (p<0.001). All lenses were tested in an identical manner, soaked in a PBS (phosphate-buffered saline solution) for 16 hours +/- 2 hours (p<0.001). ^ Based on an in vitro study on TOTAL30, Biofinity, Ultra, ACUVUE OASYS and ACUVUE VITA sphere lenses wherein wettability was measured using the iDDrop System (p<0.05). All lenses were tested in an identical manner, soaked in a PBS (phosphate-buffered saline solution) for 16 hours plus/minus 2 hours (p<0.05).
REFERENCES: 1. Monadic Claim Trial support. Alcon Data on file, 2024. 2. In a clinical study wherein patients (n=66) used AOSEPT solution for nightly cleaning, disinfecting, and storing; Alcon data on file, 2021. 3. Perez-Gomez I, Giles T. European survey of contact lens wearers and eye care professionals on satisfaction with a new water gradient daily disposable contact lens. Clin Optom. 2014;6:17-23. 4. In a clinical study where n=77; Alcon data on file, 2021. 5. Thekveli S, Qui Y, Kapoor Y, et al. Structure-property relationship of delefilcon A lenses. Contact Lens Anterior Eye. 2012;35(Suppl 1):e14. 6. Angelini TE, Nixon RM, Dunn AC, et al. Viscoelasticity and mesh-size at the surface of hydrogels characterized with microrheology. Invest Ophthalmol Vis Sci. 2013;54:E-abstract 500. 7. In vitro analysis of lens oxygen permeability, water content, and surface imaging; Alcon data on file, 2021. 8. In vitro analysis of lehfilcon A contact lenses outermost surface softness and correlation with water content; Alcon data on file, 2021. 9. Based on an in vitro study on unworn DAILIES TOTAL1® and competitive sphere lenses (1-DAY ACUVUE MOIST, MyDay and clariti 1day) using average iDDrop water break-up time (WBUT); Alcon data on file, 2019. 10. Based on an in vitro study on unworn ACUVUE OASYS 1-DAY and ACUVUE TrueEye sphere lenses using average iDDrop water break-up time (WBUT); Alcon data on file, 2019. 11. Based on an in vitro study on unworn Infuse sphere lenses testing average iDDrop water break-up time (WBUT) and surface softness; Alcon data on file, 2020. 12. Based on an in vitro study on unworn DAILIES AquaComfort PLUS sphere and BioTrue ONEday sphere lenses using average iDDrop water break-up time (WBUT); Alcon data on file, 2019. 13. Based on an in vitro study on unworn ACUVUE OASYS MAX 1-DAY sphere lenses using average iDDrop water break-up time (WBUT); Alcon data on file, 2022. 14. Based on in vitro studies of unworn TOTAL30 and competitive sphere lenses (Biofinity, Ultra, ACUVUE OASYS and ACUVUE VITA) using average iDDrop water break-up time (WBUT); Alcon data on file, 2021.